The many symptoms of Parkinson’s disease are a result from the loss of the colored dopamine secreting cells and the loss of the chemical in your body called melanin; these two things are secreted in the same cells. The cells are in the body’s pars compacta region and it is in the black substance area. These neurons lose the leads to be controlled.

The direct pathway allows movement and the indirect pathways restrict movements, the loss of these cells ultimately lead to a hypokentic disorder which in turn immobilizes movement. The lack of the chemical dopamine can end up in an increased lack of movement of the lateral nucleus of the thalamus.

There are four main dopamine pathways that lead to the brain. They are the Nigrostiatal pathways, this pathway determines the movement and it is the first hit by the Parkinson’s. The Mesocortical Pathway, The Mesolimbic Pathway and the Tuberinfundibular Pathway. These three pathways are involved with emotional response. They also reflect the sensory process and maternal behavior.

The parts of the brain that has these cells are lost due to Parkinson’s may have an unnatural amount of the protein alpha-synuclein. Too much of these proteins may have resulted in the damaged cells. Too much protein in the body is just not good in general. You need proteins in food but too much in the cells can assist in damaging them.

Another reason for the damages cells is a highly excessive amount of Iron, if the blood has too much iron then the blood cells becomes toxic. The iron and the other nutrient metals called Transitional metals like copper can bind the neuromelanin in the diseases neuron of the black substance. Right now, medications can control the symptoms but nothing can repair the damaged cells.